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KMID : 0363320190400040663
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Journal of Korean Oriental Internal Medicine
2019 Volume.40 No. 4 p.663 ~ p.674
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The Effect of Banhasasim-tang in the Treatment of Chemotherapy-induced Symptoms: A Systematic Review
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Ahn Su-Bin
Lee Ga-Young
Hwang Hyeon-Ho
Jeong Min-Jeong
Jang In-Soo
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Abstract
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Objective: The purpose of this study was to investigate (using a systematic review) the effect of Banhasasim-tang in the treatment of chemotherapy-induced symptoms.
Method: A systematic review was conducted to identify the effect of Banhasasim-tang for chemotherapy-induced symptoms. Electronic databases were used, including such as PubMed, Cochrane, CNKI, Wanfang, CiNii, J-STAGE, NDSL, and OASIS. Among others, the main search terms included “cancer”, “Banhasasim-tang”, “Banxia Xiexin Tang”, and “Hangeshashin-to”. This study only included randomized controlled trials (RCTs).
Results: A total of 14 RCTs were selected. They all identified the effect of Banhasasim-tang in the treatment of chemotherapy- induced symptoms such as nausea, vomiting, and diarrhea. In addition, five of the studies evaluated the preventive effect of Banhasasim-tang on the symptoms.
Conclusion: An analysis of 14 RCTs showed that Banhasasim-tang for chemotherapy-induced symptoms might be effective not only for treatment but also for prevention. However, due to the low quality and number of the selected original articles, the significance of this conclusion is somewhat limited. It is hoped that more systematic and rigorous clinical trials will be conducted.
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KEYWORD
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cancer, Banhasasim-tang, chemotherapy, systematic review
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